Senior Microbiologist

This role is with Allozymes a startup supported by SGInnovate.

At Allozymes, we are building the next generation enzyme engineering platform to deliver groundbreaking technological developments in the field of synthetic biology, industrial enzymes and their applications. Enzymes are an engine of the cell that empowers all the reactions in nature and in modern life they play a key role in 100s of industrial applications, from creation of cheese and wine all the way to medicine. However, finding the right enzymes and improving its performance is still a key challenge. The process of enzyme engineering is very slow, complicated and super expensive. At Allozymes we are solving all these issues with our proprietary technology. We engineer enzymes 10X faster with 200X higher chance of success compared to the conventional technologies (Robotic). We are confident that we can create products and services that will have a huge impact for the sustainable future of food, cosmetics and Pharma industries. Read in TechCrunch and Compasslist about our vision.

Allozymes is hiring a distinctive Senior Scientist into its Biology team. This team is responsible for developing novel enzymes and microbial processes to produce chemicals and natural compounds. The scientist will lead the activities involved in the development of novel and optimized strains for various purposes. Working in a highly collaborative and dynamic environment, this role has the opportunity to interact with other scientists, automation and process engineers to achieve these goals.

Duties & Responsibilities:

• Functional expression of enzyme families and classes
• Employ genetic engineering methodologies and tools, e.g. DNA assembly, transformation, integration, sequencing, bioinformatics, etc
• Pathway analysis, assembly and testing to produce target products
• Strain engineering to optimize production of target natural compounds and chemicals
• Understanding of cellular physiology, metabolism and pathways for a variety of eukaryotic and prokaryotic microbes, e.g. on processes associated with target molecule production, including redox metabolism, energy usage, product transport, impact on growth and health of organism, etc.
• Work closely with process engineers to ensure scalability of the process
• Competent in using statistics and bioinformatic tools to strengthen the experimental design and enable robust data analysis
• Systematic & problem-solving approach to projects

 
Qualifications and Experience:

• PhD in microbiology, synthetic biology, metabolic engineering, molecular biology or other relevant disciplines
• 4+ years of industrial biotech experience
• Deep experience in enzyme catalysis
• Deep experience in functional enzyme expression in microbial hosts
• Deep experience in metabolic engineering of microbes for production of natural products and/or secondary metabolism and small molecules
• Experience in protein engineering or directed evolution
• Strong hands-on experience using wet lab facilities

 Allozymes offers a comprehensive benefits package including a competitive salary, insurance, and a unique growth opportunity.

Interested applicants may apply directly on STARS https://stars.sginnovate.com/viewrole?type=tm&jobid=M-2021-ALLOZYMES-971