Synthego is hiring a

Senior Full Stack Mechatronics Engineer

Redwood City, United States

We are looking for a Senior Full Stack Mechatronics Engineer to join our team and help create the world’s first fully automated cloud-enabled molecular biology lab.

This position will own numerous projects, help build the tools and systems to enable industrial-scale molecular biology research, and bring automation to genome engineering.



Mechanical -

  • Mechanical design of scientific instruments in an industrial automation context
  • Generating P&ID, manufacturing drawings, electrical wiring diagrams


Electronics -

  • Designing new PCBs and revising existing PCBs
  • Specifying scalable electric architecture of off-the-shelf components for Synthego’s industrial automation needs
  • Developing novel, miniaturized, liquid level sensor technology that’s massively parallel - think 1,000+ individual channels
  • Generating electrical wiring diagrams for automated instrumentation & 3D modeling of harnesses


Software -

  • Writing test software in Python to conduct functional tests of first articles and prototypes as well as debugging and modifying existing instrument level code



  • 5+ years of experience in PCB design and mechanical design
  • 2+ year of experience in the automation space or instrument design or systems engineering
  • You have had a very high level of ownership in the projects you worked on
  • You have an extensive portfolio of badass projects to show us
  • You have a knack for cross-disciplinary problem-solving
  • You are a fast-paced self-starter who contributes innovative ideas
  • You love to work in a fast-paced, innovative and collaborative environment
  • You have good communication skills and a constructive team dynamic mindset
  • You are skilled at methodical self-management and project-management
  • You have humor :-)
  • BS/MS in Mechatronics or EE and related work experience
  • Bonus if you have previous experience in Biotech


Mechanical Design Skills -

    • SolidWorks, SolidWorks, SolidWorks
    • SolidWorks Electrical - Generating electrical wiring diagrams, 3D modeling of harnesses, P&ID diagrams


Electronics Skills -

    • PCB Design (Altium Design, KiCAD)
      • 2-4 layer boards
      • Design for assembly (Fiducials, generating position files, etc.)
      • Examples: I/O banks, ADC+DAC banks, PWM, RS232, I2C, beaglebone capes
    • Instrumentation
      • Sensor characterization
      • Sensor calibration of linear and nonlinear sensors
    • Industrial Automation
      • SolidWorks Electrical - 3D harness modelling, wiring diagrams, P&ID
      • Motion control (servos, steppers)
      • Digital & analog I/O banks
      • Solid understanding of the pro and cons of various bus systems (e.g. CAN, Modbus, Ethernet
    • Strong Fundamental Electronics
      • Mitigating EMI in noisy factory floor environments
    • Strong Understanding of Fundamental Signal Processing
      • 1st-Order Systems
      • Basic Continuous and Discrete-Time Filter Design
      • PID Controller Design
    • Strong troubleshooting experience with electromechanical and pneumatic systems
    • Soldering
    • Rapid iteration prototyping


Software Skills -

    • 3+ years of experience with Python
    • Fluent with Git Version Control, Hierarchical design, and object-oriented programming
    • Fluent with Linux Command Linux


Company Perks & Benefits

  • Competitive salary 
  • Generous equity at an early stage company
  • Tax-exempt medical insurance reimbursement
  • Fully stocked kitchen and snacks
  • Free catered lunches and dinners



Synthego is turning molecular biology into an information science. We're building hardware facilities that abstract biological syntheses and research into software.

Our vision is to bring automation to genome engineering, enabling scientists to run their own fully-automated laboratory at low cost, performing millions of controlled, repeatable experiments per day without human error.

Founded by former SpaceX engineers, Synthego is a leading provider of genome engineering solutions.  The company’s flagship product, CRISPRevolution, is a portfolio of synthetic RNA designed for CRISPR genome editing and research.

We are venture backed by Founders Fund, Menlo Ventures, 8VC, and WI Harper. 


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