Senior Director / Executive Director, Clinical Operations

In this role, you will lead end-to-end clinical operations for oncology programs while building the foundational infrastructure needed for scalable growth.

• Lead execution of Phase 1/2 oncology clinical trials, ensuring timely, high-quality, and budget-compliant delivery
• Build and scale the clinical operations function, including hiring, onboarding, and mentoring initial team members
• Develop and implement SOPs, operational frameworks, and systems to support clinical trial execution and future expansion
• Oversee clinical trial budgeting, forecasting, and resource allocation, ensuring financial discipline and risk management
• Manage CROs and external vendors, including selection, contract negotiation, oversight, and performance management
• Drive study planning, risk mitigation, and scenario planning to proactively address operational challenges
• Collaborate cross-functionally with clinical, scientific, and executive stakeholders to align strategy and execution

Requirements:

This position requires deep experience in clinical operations within biotech or pharmaceutical environments, particularly in oncology and early-phase trials.

• 10+ years of experience in pharma or biotech clinical operations, including at least 5+ years in oncology (Phase 1 and 2 studies required)
• Proven experience leading end-to-end global clinical trials, including startup, execution, and database lock
• Track record of building and scaling clinical operations teams in early-stage or high-growth biotech environments
• Strong expertise in CRO and vendor management, including contracting and performance oversight
• Solid financial acumen with experience in budgeting, forecasting, and resource planning for clinical programs
• Strong analytical and organizational skills, with proficiency in tools such as Excel, MS Project, or Smartsheet
• Ability to operate in high-ambiguity environments with strong decision-making and problem-solving capabilities
• Excellent communication and executive presence, with experience presenting to senior leadership and stakeholders
• Hands-on leadership style with the ability to balance strategic thinking and operational execution

Benefits:

• Competitive base salary range of $250,000 – $300,000 USD
• Equity participation as part of total compensation package
• Comprehensive medical, dental, and vision insurance
• 401(k) retirement plan with company match
• Short-term and long-term disability coverage
• Flexible paid time off (PTO) and remote-first work model
• Work-from-home stipend to support remote setup
• Professional development, mentorship, and growth opportunities
• Exposure to cutting-edge oncology innovation and high-impact clinical programs

We use an AI-powered matching process to ensure your application is reviewed quickly, objectively, and fairly against the role's core requirements. Our system identifies the top-fitting candidates, and this shortlist is then shared directly with the hiring company. The final decision and next steps (interviews, assessments) are managed by their internal team.

We appreciate your interest and wish you the best!

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