Research Associate II/III, In Vivo
TLDR
Independently conduct in vivo studies, including tumor models and diverse agent administration, to support the company's goals.
Job Summary:
The purpose of the In Vivo Research Associate II/III position is to independently conduct in vivo studies in support of the Company's goals and objectives.
Responsibilities:
- Works closely with Study Directors, Study Coordinators and cross functional team members to ensure all assigned studies are conducted in accordance with study protocols, standard operating procedures and company policies
- Collection of body weight data
- Collection of tumor volume measurements
- Collect tissue samples and process for shipment to sponsor as well as internal purposes
- Responsible for the tracking of samples and shipping of samples to sponsor companies
- Preparation of animals for procedures, including shaving, ear tagging and other tasks as directed
- Performance of clinical observations and humane euthanasia in mice
- Collect relevant data and provide feedback to team members regarding progress of assigned projects
- Perform advanced in vivo procedures (including sample collection, surgeries.) with minimal direct supervision required
- May be trained on more complex procedures
- Perform subcutaneous inoculations
- Administer therapeutic agents through different routes of administration, including IP, PO, SC, IM, ID, IN and IV
- Providing general group support by cleaning, general supply stocking and sample shipping
- Responsible for tracking time spent on projects (project logs)
Minimum Requirements:
- Bachelor's degree is required
- 2-3 years of experience handling animals in a Vivarium environment is required
- Comfortable working in a laboratory animal research environment
- Demonstrated ability to perform a minimum of three of the following in vivo oncology tumor models in mice:
- Animal handling
- Tumor implantation
- Tumor measurement
- Gross necropsy
- Simple drug preparation
- Drug administration by various routes
- Minor survival surgery
- In-life and terminal bleeds
- Demonstrated sense of integrity and confidentiality
- Planning, organizational skills and flexibility in a reactive environment
- Demonstrated accountability and responsibility for own work
- Ability to follow standard operating procedures, observe safety and security procedures
- Able to troubleshoot effectively and solve problems with supervision
Preferred Requirements:
- AALAS certification at ALAT level or higher is preferred
Crown Bioscience is committed to a diverse and inclusive workplace. Crown Bioscience is an equal opportunity employer and does not discriminate based on race, national origin, gender, gender identity, sexual orientation, protected veteran status, disability, age, or other legally protected status.
Crown Bioscience is a global contract research organization focused on oncology and immuno-oncology, providing preclinical and translational platforms to streamline drug discovery and development. With innovative tumor organoid services and the largest commercially available patient-derived xenograft collection, Crown empowers clients to identify superior clinical candidates for effective patient treatment.